@font-face {
  font-family: 'Instrument Serif';
  font-style: normal;
  font-weight: 400;
  font-display: optional;
  src: url(/fonts/instrument-0.woff2) format('woff2');
}

@font-face {
  font-family: 'DM Sans';
  font-style: normal;
  font-weight: 400;
  font-display: optional;
  src: url(/fonts/sans-0.woff2) format('woff2');
}
@font-face {
  font-family: 'DM Sans';
  font-style: normal;
  font-weight: 700;
  font-display: optional;
  src: url(/fonts/sans-1.woff2) format('woff2');
}

@font-face {
  font-family: 'IBM Plex Mono';
  font-style: normal;
  font-weight: 400;
  font-display: optional;
  src: url(/fonts/mono-0.woff2) format('woff2');
}
body{--paper:#f5f2ff;--ink:#27213d;--accent:#603fd2;--display:"Instrument Serif",Georgia,serif;--line:#d8d5ce;--muted:#535a60;--panel:#ffffff;--button-ink:#ffffff;}
* {
    box-sizing:border-box
}
html {
    scroll-behavior:smooth
}
body {
    margin:0;
    background:var(--paper);
    color:var(--ink);
    font:17px/1.65 "DM Sans",Arial,sans-serif
}
a {
    color:inherit;
    text-underline-offset:4px
}
a:hover {
    color:var(--accent)
}
button,input,textarea,select {
    font:inherit
}
button,.button {
    cursor:pointer;
    display:inline-block;
    padding:12px 20px;
    border:1px solid var(--accent);
    background:var(--accent);
    color:var(--button-ink,#fff);
    text-decoration:none;
    font-weight:700;
    border-radius:3px
}
button:hover,.button:hover {
    filter:brightness(.93);
    color:var(--button-ink,#fff)
}
:focus-visible {
    outline:3px solid var(--accent);
    outline-offset:5px
}
.skip {
    position:absolute;
    left:10px;
    top:-80px;
    background:var(--paper);
    z-index:5
}
.skip:focus {
    top:10px
}
.wrap {
    max-width:1220px;
    margin:auto;
    padding:0 40px
}
header {
    border-bottom:1px solid var(--line);
    padding:25px 0
}
header .wrap {
    display:flex;
    align-items:center;
    justify-content:space-between;
    gap:24px
}
.brand {
    font-size:22px;
    font-weight:800;
    letter-spacing:-.8px;
    text-decoration:none
}
nav {
    display:flex;
    gap:25px;
    font-size:14px;
    align-items:center
}
nav a {
    text-decoration:none
}
main {
    min-height:70vh
}
.eyebrow {
    font-size:12px;
    text-transform:uppercase;
    letter-spacing:2px;
    font-weight:700;
    color:var(--accent)
}
h1,h2,h3 {
    font-family:var(--display);
    line-height:1.1;
    font-weight:500;
    letter-spacing:-1.6px
}
h1 {
    font-size:clamp(46px,6.8vw,86px);
    max-width:900px;
    margin:22px 0
}
h2 {
    font-size:clamp(30px,3vw,44px);
    margin:0 0 24px
}
h3 {
    font-size:26px;
    letter-spacing:-.6px;
    margin:0 0 14px
}
p {
    margin:0 0 22px
}
.intro {
    font-size:20px;
    max-width:640px;
    color:var(--muted)
}
.hero {
    padding:80px 0 70px
}
.hero-grid {
    display:grid;
    grid-template-columns:1.25fr 1fr;
    gap:65px;
    align-items:center
}
.hero-grid h1 {
    font-size:clamp(45px,5.7vw,74px)
}
.hero .button {
    margin-top:12px
}
.section {
    padding:60px 0;
    border-top:1px solid var(--line)
}
.section-head {
    display:flex;
    align-items:end;
    justify-content:space-between;
    gap:20px;
    margin-bottom:24px
}
.section-head h2 {
    margin:0
}
.cards {
    display:grid;
    grid-template-columns:repeat(3,1fr);
    gap:25px
}
.card {
    display:block;
    text-decoration:none;
    padding:30px 0;
    border-top:2px solid var(--accent)
}
.card p {
    font-size:16px;
    color:var(--muted)
}
.arrow {
    font-size:22px;
    color:var(--accent)
}
.tool-callout {
    padding:35px;
    background:var(--panel);
    border:1px solid var(--line);
    display:flex;
    align-items:center;
    justify-content:space-between;
    gap:30px
}
.tool-callout p {
    margin:0;
    max-width:640px
}
.reading {
    max-width:790px;
    padding-top:60px;
    padding-bottom:80px
}
.reading h1 {
    font-size:clamp(38px,5vw,58px)
}
.reading h2 {
    font-size:30px;
    margin-top:48px;
    letter-spacing:-.6px
}
.reading .summary {
    font-size:21px;
    color:var(--muted)
}
.meta {
    font-size:13px;
    color:var(--muted)
}
.reading p {
    line-height:1.85
}
.toc {
    padding:24px;
    background:var(--panel);
    border-left:3px solid var(--accent);
    margin:30px 0
}
.toc a {
    display:block;
    margin:8px 0
}
.sources li {
    margin:12px 0;
    font-size:15px
}
.next-step {
    margin-top:48px;
    padding:28px;
    border:1px solid var(--line)
}
.next-step h2 {
    margin:0 0 15px;
    font-size:27px
}
.next-step .disclosure {
    font-size:13px;
    margin-top:15px;
    margin-bottom:0
}
.back {
    font-size:14px
}
.tool-page {
    padding-top:55px;
    padding-bottom:65px
}
.tool-page h1 {
    font-size:clamp(38px,5vw,62px)
}
.tool-shell {
    margin-top:35px;
    background:var(--panel);
    border:1px solid var(--line);
    padding:35px;
    border-radius:4px;
    overflow:hidden
}
.tool-shell h2 {
    font-size:30px;
    letter-spacing:-.5px
}
.tool-shell h3 {
    font:700 19px/1.4 "DM Sans",Arial,sans-serif;
    letter-spacing:0
}
.tool-grid {
    display:grid;
    grid-template-columns:1fr 1fr;
    gap:25px
}
.field {
    margin:15px 0
}
.field label,label {
    display:block;
    margin-bottom:7px
}
.field input,input[type=text],input[type=number],textarea,select {
    width:100%;
    padding:12px;
    border:1px solid var(--line);
    color:var(--ink);
    background:var(--paper);
    border-radius:3px
}
input[type=checkbox] {
    accent-color:var(--accent);
    width:18px;
    height:18px;
    vertical-align:middle
}
input[type=range] {
    width:100%;
    accent-color:var(--accent)
}
fieldset {
    border:1px solid var(--line);
    margin:20px 0;
    padding:20px
}
legend {
    padding:0 8px;
    font-weight:bold
}
.result {
    padding:22px;
    margin:20px 0;
    border-left:3px solid var(--accent);
    background:var(--paper)
}
canvas {
    max-width:100%;
    height:auto
}
.tool-shell table {
    width:100%;
    border-collapse:collapse;
    font-size:15px
}
.tool-shell td,.tool-shell th {
    padding:8px;
    text-align:left;
    border-bottom:1px solid var(--line)
}
.tool-shell button {
    margin:5px 5px 5px 0
}
output {
    display:block
}
.tool-shell pre {
    white-space:pre-wrap;
    overflow-wrap:anywhere
}
footer {
    padding:40px 0;
    border-top:1px solid var(--line);
    font-size:13px;
    color:var(--muted)
}
footer .footer-top {
    display:flex;
    justify-content:space-between;
    gap:25px;
    margin-bottom:25px
}
footer a {
    margin-right:20px
}
footer p {
    max-width:800px;
    margin-bottom:10px
}
.document {
    background:#fffcf5;
    color:#302b25;
    border:1px solid #d5cbbb;
    box-shadow:13px 13px 0 #e5dbcb;
    padding:35px;
    transform:rotate(2deg)
}
.document h2 {
    font-size:25px;
    border-bottom:2px solid #302b25;
    padding-bottom:20px
}
.docrow {
    display:flex;
    justify-content:space-between;
    gap:20px;
    padding:14px 0;
    border-bottom:1px solid #ddd3c3;
    font-size:14px
}
.note {
    font-size:12px;
    color:var(--muted);
    margin-top:15px
}
.trace {
    position:relative;
    height:260px;
    display:flex;
    align-items:end;
    gap:5px;
    padding:20px;
    border-bottom:1px solid var(--accent);
    background:repeating-linear-gradient(0deg,transparent,transparent 49px,#ffffff0a 50px)
}
.trace i {
    display:block;
    flex:1;
    background:var(--accent);
    min-height:2px;
    border-radius:12px 12px 0 0
}
.trace-label {
    font:12px monospace;
    letter-spacing:2px;
    margin-top:15px
}
.term-board {
    display:grid;
    gap:14px;
    transform:rotate(-2deg)
}
.term-tile {
    padding:24px;
    background:white;
    border:1px solid #d9d0ef;
    box-shadow:4px 4px 0 #d9d0ef;
    display:flex;
    justify-content:space-between;
    gap:20px
}
.term-tile strong {
    font:28px "Instrument Serif",Georgia,serif
}
.term-tile span {
    font-size:14px;
    align-self:center
}
.briefing {
    border-top:8px solid var(--accent);
    background:white;
    padding:28px;
    box-shadow:12px 12px 0 #e7e2d7
}
.briefing dl {
    margin:0
}
.briefing dt {
    font-size:12px;
    text-transform:uppercase;
    letter-spacing:1px;
    margin-top:20px;
    color:#a24322
}
.briefing dd {
    margin:5px 0 20px;
    font-size:20px
}
.data-grid {
    background-color:#fff;
    background-image:linear-gradient(#dceaf1 1px,transparent 1px),linear-gradient(90deg,#dceaf1 1px,transparent 1px);
    background-size:25px 25px;
    border:1px solid #c4dae5;
    padding:35px
}
.data-grid .num {
    font:70px "Instrument Serif",Georgia,serif;
    color:#12618a;
    line-height:1.1
}
.data-grid hr {
    border:0;
    border-top:1px solid #a7c3d2
}
.data-grid p {
    font:14px monospace;
    margin:12px 0
}
.topic-list {
    display:grid;
    grid-template-columns:220px 1fr;
    gap:30px;
    margin-top:40px
}
.topic-list aside {
    border-right:1px solid var(--line);
    padding-right:25px
}
.topic-list .card {
    display:grid;
    grid-template-columns:1fr 1fr;
    gap:30px;
    padding:25px 0
}
.topic-list .card h3 {
    font-size:30px
}
.dictionary .cards {
    display:block
}
.dictionary .card {
    display:grid;
    grid-template-columns:1fr 1fr 30px;
    gap:30px;
    padding:28px 0
}
.dictionary .card p {
    margin:0
}
.methods h1,.methods h2 {
    font-weight:700;
    letter-spacing:-2px
}
.methods .card {
    background:#143238;
    padding:28px;
    border:1px solid #2c5055
}
.methods .button {
    color:#0e2529
}
.methods .hero {
    padding-top:65px
}
.methods .tool-shell {
    --accent:#135544;
    --paper:#f2faf5;
    --ink:#172e25;
    --line:#bdd4c6;
    --muted:#435c4e;
    color:var(--ink);
    background:#f9fcfa;
    --button-ink:#fff
}
.methods .tool-shell button {
    color:white
}
.sourcing h1,.sourcing h2 {
    font-weight:750
}
.sourcing .brand {
    font-family:"DM Sans",Arial,sans-serif
}
.sourcing header {
    border-top:7px solid var(--accent)
}
.data .hero {
    background:linear-gradient(120deg,#e1f0f6,transparent)
}
.data .card {
    border-top:0;
    border-left:3px solid var(--accent);
    padding:0 24px
}
.coa .brand,.peptides .brand,.data .brand {
    font-family:"Instrument Serif",Georgia,serif;
    font-weight:500
}
.peptides .hero h1 {
    max-width:650px
}
.peptides .card {
    border-top:1px solid var(--line)
}
.peptides .button {
    border-radius:30px
}
.coa .section-head {
    border-bottom:1px solid var(--ink);
    padding-bottom:20px
}
.table-wrap {
    overflow:auto
}
table {
    border-collapse:collapse
}
th,td {
    text-align:left;
    padding:12px;
    border-bottom:1px solid var(--line)
}
@media(max-width:760px) {
    .wrap {
    padding-left:22px;
    padding-right:22px
}
header .wrap {
    align-items:start;
    flex-direction:column;
    gap:15px
}
nav {
    gap:18px;
    flex-wrap:wrap
}
.hero {
    padding:45px 0
}
.hero-grid {
    grid-template-columns:1fr;
    gap:40px
}
.hero-grid h1 {
    font-size:48px
}
.cards,.tool-grid {
    grid-template-columns:1fr
}
.section {
    padding:40px 0
}
.tool-callout {
    display:block;
    padding:25px
}
.tool-callout .button {
    margin-top:20px
}
.section-head {
    align-items:start;
    flex-direction:column
}
.tool-shell {
    padding:20px
}
.topic-list {
    grid-template-columns:1fr
}
.topic-list aside {
    border:0
}
.topic-list .card,.dictionary .card {
    display:block
}
.topic-list .card p,.dictionary .card p {
    margin-top:15px
}
.document {
    transform:none
}
.term-board {
    transform:none
}
footer .footer-top {
    display:block
}
footer a {
    display:inline-block;
    margin-bottom:10px
}
.reading h1 {
    font-size:40px
}
.data-grid .num {
    font-size:55px
}

}
@media(prefers-reduced-motion:reduce) {
    html {
    scroll-behavior:auto
}

}
@media print {
    header,footer,.button,button,.next-step,.skip {
    display:none
}
body {
    background:#fff;
    color:#000;
    --paper:#fff;
    --panel:#fff;
    --ink:#000;
    --muted:#333;
    --accent:#333;
    --line:#aaa
}
.wrap {
    max-width:none
}
.tool-shell {
    border:0;
    padding:0
}
a {
    color:#000
}

}


/* Reading navigation remains vertical on every screen size. */
.toc {
    display: block;
}
.breadcrumbs {
    flex-wrap: wrap;
    gap: 10px;
    font-size: 14px;
    margin-bottom: 24px;
}
.direct-answer {
    border-left: 3px solid var(--accent);
    padding: 20px 24px;
    background: var(--panel);
    font-size: 20px;
}
.section-sources {
    font-size: 13px;
    color: var(--muted);
}
.reading .section-sources {
    line-height: 1.6;
}
.related {
    margin-top: 45px;
    padding-top: 18px;
    border-top: 1px solid var(--line);
}
.related li, .downloads li {
    margin: 15px 0;
}
.downloads p {
    margin-top: 6px;
    color: var(--muted);
    font-size: 16px;
}
header nav {
    flex-wrap: wrap;
    justify-content: flex-end;
}
@media (max-width: 760px) {
    header nav {
        justify-content: flex-start;
    }
    .breadcrumbs {
        font-size: 13px;
    }
}
.exercise .scroll {
    overflow-x: auto;
    max-width: 100%;
}
.exercise table {
    font-size: 15px;
    line-height: 1.5;
    width: 100%;
}
.exercise caption {
    text-align: left;
    font-weight: 700;
    margin: 14px 0;
}
.exercise svg {
    max-width: 100%;
    height: auto;
}
.exercise figure {
    margin: 24px 0;
}
.exercise code {
    overflow-wrap: anywhere;
}
.exercise .lesson-plan {
    padding: 20px 24px;
    border: 1px solid var(--line);
    margin: 30px 0;
}
.exercise .lesson-plan h2 { margin-top: 0; }
.exercise .trace-legend li { margin: 0; }
.exercise .instructor-notes {
    border-top: 1px solid var(--line);
    margin-top: 24px;
    padding-top: 12px;
}
@media print {
    .reading { padding-top: 0; }
    .reading h1 { font-size: 28pt; }
    .toc,.breadcrumbs,.related { display:none; }
    .exercise .scroll,.table-scroll { overflow:visible; }
    .exercise tr,.exercise figure { break-inside:avoid; }
    .exercise .answer-key { break-before:page; }
    .table-scroll table { min-width:0; }
    h2,h3 { break-after:avoid; }
}

.table-scroll{overflow-x:auto;max-width:100%;margin:1.6rem 0}.table-scroll table{border-collapse:collapse;min-width:34rem;width:100%;font-size:.93rem}.table-scroll th,.table-scroll td{text-align:left;border-bottom:1px solid var(--line);padding:.75rem;vertical-align:top}.table-scroll th{background:var(--panel)}.reading pre{overflow-x:auto;padding:1.3rem;background:var(--panel);border:1px solid var(--line)}.study code{overflow-wrap:anywhere}.study .downloads{columns:2;column-gap:2rem}.study .downloads li{break-inside:avoid;margin-bottom:.8rem}@media(max-width:650px){.study .downloads{columns:1}}

.article-figure { margin: 2rem 0; }
.article-figure > a { display: block; border: 1px solid var(--line); border-radius: 10px; overflow: hidden; }
.article-figure img { display: block; width: 100%; height: auto; }
.article-figure figcaption { margin-top: .75rem; font-size: .9rem; line-height: 1.55; color: var(--muted); }
.article-figure figcaption a { white-space: normal; }
@media print { .article-figure { break-inside: avoid; } .article-figure figcaption a { display: none; } }

.trace-examples {
    display: grid;
    grid-template-columns: repeat(auto-fit, minmax(min(100%, 16rem), 1fr));
    gap: 1rem;
}
.trace-examples figure {
    min-width: 0;
    margin: 0;
}
.trace-examples svg {
    display: block;
    width: 100%;
    height: auto;
}
.trace-examples figcaption {
    color: var(--muted);
    font-size: .9rem;
}
.table-scroll:focus-visible {
    outline: 2px solid var(--accent);
    outline-offset: 3px;
}
.tool-shell .table-scroll th {
    color: var(--ink);
}